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Title A Tale Of Two Cities. This Is Significant Because

Title: A Tale of Two Cities. This is significant because A Tale of Two Cities tells the story of two cities - London and Paris. Author’s Name: Charles Dickens Life and Country of Origin: Charles Dickens was born on February 7, 1812, in Portsmouth, England. He grew up quite poor, despite his families best efforts, and it had a great impact on him. Which is quite similar to the oppression the French felt during the French Revolution. (biography.com) Setting: The story takes place in the cities of London and Paris from 1775-1792. Paris is portrayed as a city where the corruption of the upper class leads revolutionaries to rise up against them, but the violence that replaces that corruption is not much better. London is portrayed as somewhat†¦show more content†¦Unlike her husband, she proves to be truly evil because her desire for blood-shed knows no bounds. Monsieur Defarge - Monsieur Defarge was a wine shop owner and a intelligent and committed revolutionary. He used to be servant for Doctor Manette. Even though Monsieur Defarge wants a â€Å"better France† he is not as bloodthirsty as his wife. Jarvis Lorry - A old business man who works for Telson’s bank. He is a trustworthy person and a loyal friend to the Manette’s. Miss Pross - The servant who raised Lucie. She is very loyal to Lucie. Because of this she provides a foil to Madame Defarge, who symbolizes violent chaos that is associated with the revolution. Marquis Evremonde - A French aristocrat and Charles Darnay’s uncle. He shows absolutely no regard for human life and wishes that the world be free of peasants. He is cruel, and during the story will not help an old widow pay for her husband’s grave marker. He also runs over a child and feel’s no remorse. He is killed in his sleep because of these acts of cruelness. Mr. Stryver - A very ambitious lawyer, who â€Å"stryves† to climb the social ladder. He is a contrast to Sydney Carton. Themes and Ideas: The necessity of sacrifice - A theme in a tale of two cities is that sacrifice is necessary in order to be happy.We see this theme on both a personal level with Sydney Carton, and a national level with the French Revolution. Example: In order for Carton to transform into aShow MoreRelatedA Tale of Two Cities, by Charles Dickens1381 Words   |  6 PagesOf the extraordinary amount of literary devices available to authors, Charles Dickens uses quite a few in his novel A Tale of Two Cities, which is set during the French Revolution. One of his more distinctive devices is character foils. The five sets of foils are Carton and Darnay, Carton and Stryver, Darnay and the Marquis de Evremonde, Madame Defarge, and Mr. Lorry and Jerry Cruncher. 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Lipid Profiles In Postmenopausal Women Health And Social Care Essay Free Essays

string(158) " Writers concluded that Letrozole modestly decreases TC at 3 months ; nevertheless, the consequence is non sustained throughout the intervention clip period\." Aim: Aromatase inhibitors are presently used in accessory to the former gold criterion Tamoxifen or as first line hormone therapy in postmenopausal adult females with chest malignant neoplastic disease. Suppressing the aromatase mechanism of action impedes the synthesis of estrogen, forestalling estrogen protection on lipid profiles. This literature reappraisal examines, discusses, and analyzes peer-reviewed published clinical tests analyzing the effects of anastrozole, exemestane, and letrozole, on lipid profiles in postmenopausal adult females with estrogen dependent chest malignant neoplastic disease. We will write a custom essay sample on Lipid Profiles In Postmenopausal Women Health And Social Care Essay or any similar topic only for you Order Now Decisions: Overall, there are minimum, if any, unfavourable effects of aromatase inhibitors on lipid profiles. However, restrictions of little population sizes, fluctuations in design methods, and old Tamoxifen usage, make it hard to accurately assess hazard. Long term prospective surveies utilizing big sample sizes and patients with no exposure to any other hormone intervention besides aromatase inhibitors, are needed to accurately measure if inauspicious effects on lipid profiles exist from the utilizing aromatase inhibitors. Healthcare professionals should go on to supervise lipoids in postmenopausal adult females with chest malignant neoplastic disease and develop individualized intervention programs utilizing current recommendations. Cardinal Wordss: aromatase inhibitor, chest malignant neoplastic disease, post-maturity, lipid, Anastrozole, Letrozole, Exemestane, cholesterin, and lipid metamorphosis. Aromatase Inhibitors Risk of Adverse Effects on Lipid Profiles in Postmenopausal Women with Breast Cancer: A Literature Review Introduction Breast malignant neoplastic disease pestilences about 2.5 million adult females in the United States, 1 doing it one of most prevailing signifiers of tumor that healthcare practicians dainty today. The hazard of developing chest malignant neoplastic disease increases with age, with one in 13 postmenopausal adult females developing the disease.2 Nearly 70 per centum of those postmenopausal adult females will hold a endocrine dependant ( estrogen positive ( ER+ ) , progesterone positive ( PR+ ) ) signifier of chest malignant neoplastic disease that utilizes estrogen as its chief alimentary beginning for the proliferation of the tumour. 2, 3, 4 In postmenopausal adult females, estrogen is chiefly synthesized in the peripheral tissues, chest, musculus, adipose, tegument by the enzyme aromatase.4,5 Aromatase converts adrenal androgens into estrogen via the CYP450 enzyme pathway.4, 5, 6, Suppressing aromatase and hindering this transition limits the sum of estrogen available for use by tum our cells, later forestalling growing and spread. Through this mechanism of action, steroidal ( Exemestane ) and non-steroidal ( anastrozole and letrozole ) aromatase inhibitors have shown to be extremely efficacious in the intervention of ER+/PR+ chest malignant neoplastic disease in postmenopausal adult females compared to that of Tamoxifen.5 Multiple landmark surveies ( MA.17, 2 ATAC, 7 BIG 1-98, 8 and EORTC9 ) , suggest that Tamoxifen is no longer a gilded criterion, and now recommend utilizing AIs as first line hormone therapy in these patients.5 With the spread outing usage of AIs by practicians in the intervention of endocrine dependent chest malignant neoplastic disease and the subsequent betterment in disease free endurance rates, more postmenopausal adult females are populating long plenty to see other comorbidities, such as cardiovascular disease ( CVD ) .4 Since CVD is the primary cause of mortality in postmenopausal adult females, 10 understanding the associated inauspicious effects AIs pose on cardiovascular hazard factors is pertinent. Lipid biomarkers are often assessed clinically to find a patients hazard of developing CVD. Previous epidemiologic surveies have shown that estrogen is protective and good to some cardiovascular hazard factors, specifically lipid profiles, via its direct effects on the endothelial cells found in blood vessels.6,11 Estrogen alters concentrations of lipoids in the blood ; diminishing serum concentrations of entire cholesterin ( TC ) , low-density lipoprotein ( LDL ) , and triglycerides ( TRG ) , while increasing serum concentrations of high-density lipoprotein ( HDL ) .11, 12 Therefore, it is thought that postmenopausal adult females taking AIs are deprived of this cardioprotective consequence of estrogen since its synthesis is being prevented by suppressing the aromatase transition mechanism. Therefore, the inquiry can be proposed: Make aromatase inhibitors adversely affect lipid profiles and later present an increased hazard of developing cardiovascular disease in postmenopausal adult females with ER+/PR+ chest malignant neoplastic disease? This literature reappraisal of current clinical test informations examines and assesses the usage of AIs, Exemestane ( Aromasin ) , Anastrozole ( Arimidex ) , and Letrozole ( Femara ) , on the inauspicious effects of the lipid profiles of postmenopausal adult females with ER+/PR+ chest malignant neoplastic disease. Search footings included cardiovascular, aromatase inhibitor, chest malignant neoplastic disease, post-maturity, lipid, Anastrozole, Letrozole, Exemestane, plasma lipoid, cholesterin, and lipid metamorphosis. MEDLINE in Pubmed, MEDLINE ( on EBSCO ) , and OVID were used to seek for peer-reviewed diary articles published between the old ages 2005 to 2010. Recent grounds showing the effects AIs render on the lipid profiles of postmenopausal adult females with estrogen dependent chest malignant neoplastic disease is discussed, analyzed, and reviewed in the undermentioned subdivisions. AROMATASE INHIBITORS EFFECT ON LIPID PARAMETERS Depriving chest malignant neoplastic disease stricken postmenopausal adult females of the benefit of estrogen via the AI mechanism is thought to hold damaging effects on CVD hazard factors. Several clinical tests utilizing assorted design methods have been conducted and show variable effects of AIs on the different cholesterin parametric quantities and lipoproteins. Table 1 summarizes the effects of AIs on assorted lipid biomarkers in the postmenopausal adult female with ER+/PR+ chest malignant neoplastic disease, and all surveies in the tabular array are discussed in the following subdivisions. Placebo Controlled Tests Two surveies have evaluated the consequence of AIs versus placebo on lipid biomarkers. As a secondary end point, Cigler et al13 studied the effects of Letrozole versus placebo on serum lipid parametric quantities ( TC, HDL, LDL, TRG ) in 60 seven postmenopausal adult females utilizing a random, placebo-controlled design. Lipids were measured at baseline and during the 3rd, 6th, 12th, and 24th months, and the per centum alteration from baseline was calculated for each month. Researchers noted a statistically important lessening in the TC at month 3 ( P value=0.052 ) in the Letrozole arm of the survey. The other parametric quantities ( TRG, LDL, and HDL ) measured were non significantly changed from baseline in either the Letrozole or the placebo weaponries. Writers concluded that Letrozole modestly decreases TC at 3 months ; nevertheless, the consequence is non sustained throughout the intervention clip period. You read "Lipid Profiles In Postmenopausal Women Health And Social Care Es say" in category "Essay examples"13 The cogency of consequences in the lipid part of this survey are questionable because of the imbalanced figure of participants in each intervention group, and the little population size that remained at the terminal of the 24 months ( Letrozole: 26 patients, and placebo: 16 patients ) . It is hard to measure accurate tendencies in informations with little population sizes, and consequences should be verified utilizing similar survey methods with larger population sample sizes. A confusing variable in this survey was the old usage of Tamoxifen in some patients and non others. Tamoxifen has shown to hold good effects on lipoids ; 14, 15 therefore, the consequences from patients that had antecedently taken Tamoxifen may non be a true representation of the effects of the AI entirely on lipid profiles. Another placebo controlled test utilizing different design methods was conducted by Lonning et al16 and contrasting consequences were found. The effects of Exemestane versus that of placebo on plasma lipoids in postmenopausal adult females with resectable chest malignant neoplastic disease was studied by Lonning et al.16 In a dual blind manner, one hundred 40 seven patients were indiscriminately assigned to an Exemestane intervention group or a placebo intervention group. Measurements of lipid biomarkers ( TC, HDL, LDL, TRG, ApoLipoprotein A1, lipoprotein A, ApoLipoprotein B, homocysteine ) were taken at baseline, and at the 3rd, 6th, 12th, and 24th month. Results revealed that the Exemestane intervention group had a statistically important ( P value A ; lt ; 0.001 ) lessening in HDL versus that of the placebo intervention group. Besides, a statistically important ( p=0.004 ) lessening in Apolipoprotein A1 occurred in the Exemestane intervention group versus that of the placebo intervention group. Writers concluded that the steroidal AI, exemestane has modest effects on HDL lipid biomarkers and those hazard factors for C VD should be followed overtime.16 This survey included more participants than Ciglers study ; hence, the consequences seen here may hold more cogency. Besides, a different AI was used in each test, and this variable could account for the disagreement in consequences between the two surveies. No old Tamoxifen usage was denoted in the survey by Lonning et Al ; 16 therefore, the consequences are a better representation of the effects of the AI on lipoids without confusing influences of Tamoxifen. More placebo controlled tests are necessary to to the full understand the effects of AI on lipoids in postmenopausal adult females with endocrine dependent chest malignant neoplastic disease, and to denote if a true lessening in HDL exists. The following subdivision discusses tests in which AIs were compared with Tamoxifen alternatively of a placebo as the intercession intervention groups to be assessed. Tamoxifen Comparative Tests Surveies have been conducted utilizing Tamoxifen as a comparative intervention group to that of Exemestane, and their several inauspicious effects on lipid profile alterations are discussed. The TEAM Greek bomber study17 randomized postmenopausal adult females with early chest malignant neoplastic disease into an Exemestane arm ( 77 patients ) or into a Tamoxifen arm ( 65 patients ) , and evaluated HDL, LDL, TRG, and TC at baseline, and at 12, 18, and 24 months. Results indicate that TC decreased overtime in both intervention groups ; nevertheless, those in the Tamoxifen arm had a crisp diminution at month 18 and 24, doing the difference between groups at that clip period statistically important with P value=0.020 and P value=0.0087, severally. Both interventions had a statistically important lessening in HDL ; nevertheless, the Tamoxifen group maintained higher degrees of HDL, leting for a more favourable consequence than exemestane, with a statistically important average difference ( P=0.011 ) between the intervention groups. The Tamoxifen intervention group had a important consequence on the LDL parametric quantity doing a steep lessening in values overtime. exemestane had failed to demo any important alteration on LDL. The TRG parametric quantity revealed no noticeable tendencies for either intervention regimen. Research workers concluded that Tamoxifen has a favourable consequence on TC and LDL, while Exemestane has a more indistinct consequence on lipid biomarkers.17 The lessening in HDL in this survey is in harmony with that of Lonning et al.16 One restriction is that all four lipid parametric quantities were non accounted for in all patients in each intervention group ; hence, tendencies seen in each parametric quantity may non stand for the true tendency that would be present if all values were recorded for all patients at all measurement clip periods. This survey reiterates the idea that Tamoxifen has good effects on lipoids ; accordingly, it is hard to accurately measure the hazard of AI when the comparative intervention group is Tamoxifen. 14 Though some restrictions were present in this survey, comparative consequences were seen by Francini et al14 in another test utilizing different methods than the TEAM Greek bomber survey. Francini et al14 conducted a survey in which 55 postmenopausal adult females who had antecedently been treated with no less than 2 old ages of Tamoxifen were randomized into two intervention groups: either continue Tamoxifen or exchange from Tamoxifen to Exemestane. Lipid parametric quantities were measured at baseline and at 6 and 12 months. Consequences yielded were statistically important in the Exemestane arm of the survey entirely demoing a lessening in HDL overtime ( p value A ; lt ; 0.05 ) , an addition in LDL overtime ( p value A ; lt ; 0.01 ) , and a lessening in TRG overtime ( P value A ; lt ; 0.01 ) . The differences between the Tamoxifen and Exemestane intervention group were non important except for the LDL biomarker ( p value A ; lt ; 0.05 ) . Writers concluded that the addition in LDL of the Exemestane group may be due in portion to participants being antecedently treated with Tamoxifen, which is known to hold good effects on LDL.14 Francinis survey and the TEAM Gr eek bomber study17 indicate that there was a lessening in the HDL parametric quantity in the Exemestane intervention group versus that of the Tamoxifen intervention group, proposing that AIs may hold an inauspicious consequence on HDL degrees. This lessening in HDL was besides noted in the ATENA trial18 in which Tamoxifen had been antecedently used for 5-7 old ages before the patients were assigned to have either Exemestane or no intervention, merely observation. The addition in LDL found in the survey by Francini14 was besides seen in the ATENA test ; 18 nevertheless, the TEAM Greek bomber study17 did non back up this determination. It must be kept in head that patients in the survey by Francini14 and the ATENA trial18 had antecedently been treated with Tamoxifen before get downing intervention with AIs, while patients in the TEAM Greek bomber study17 were non. Hence, the design differences could account for the fluctuation of consequences between surveies on the LDL, TRG, and TC p arametric quantities. A likewise designed survey by Montagnani et al15 exposed comparable consequences to the survey by Francini. Montagnani et al15 investigated the effects of Exemestane after anterior intervention with Tamoxifen, and indiscriminately assigned 60 eight postmenopausal adult females to go on taking Tamoxifen ( 20 milligrams daily ) or exchange to the aromatase inhibitor, Exemestane ( 25 milligrams daily ) for 2 old ages. Parameters ( TC, HDL, LDL, TRG ) were measured at baseline and at 12 and 24 months. Consequences showed that the Exemestane intercession had a important lessening in HDL, while the Tamoxifen group showed no significance in alteration from baseline. Therefore, a important difference between the intercession groups ( p value A ; lt ; 0.05 ) was noted. Besides in the Exemestane group, LDL was increased from baseline ; nevertheless, no alteration was seen in the Tamoxifen group. The between group differences were besides statistically important with a P value A ; lt ; 0.05. The Exemestane group besides had a statistically important lessening in TRG doing the between group differen ces important with a p value of A ; lt ; 0.05. The consequences found in this survey showed some similarities with those discovered by Francini et al.14 Montagnani revealed important differences between groups for HDL, LDL, and TRG parametric quantities, while Francinis survey merely showed important differences between groups for LDL. In both surveies, the aromatase inhibitor was compared with go oning Tamoxifen after the patients had already used Tamoxifen, hence some of the consequences may hold occurred from taking the good effects of Tamoxifen instead than uncovering damaging effects of the AI. Both Francini and Montagnani revealed lessenings in TRG in the Exemestane arm. This would be considered a favourable consequence of utilizing AI, but since Tamoxifen negatively affects TRG and Tamoxifen was antecedently used by the Exemestane patients, the simple remotion of the unfavourable consequence of Tamoxifen could account for the consequence. To increase the respectability of th ese findings, comparable consequences should be confirmed in likewise designed surveies utilizing larger sample population sizes without old exposure to Tamoxifen. Banerjee et al19 designed yet another survey comparing a different AI, Anastrozole, to Tamoxifen, and to a combination of Anastrozole with Tamoxifen. The IMPACT trial19 compares the effects of utilizing Anastrozole, Tamoxifen, or a combination of Anastrozole/Tamoxifen on the lipid profiles of postmenopausal adult females with chest malignant neoplastic disease. In a stage III, randomized, double-blind multicentre trial,19 three hundred 30 patients were assigned to have either Anastrozole ( 1 milligrams daily ) + Tamoxifen placebo, Tamoxifen ( 20 milligrams daily ) + Anastrozole placebo, or a combination of both ( Tamoxifen 20 mg day-to-day + Anastrozole 1mg daily ) for a period of 12 hebdomads. Measurements for TC and HDL were taken at baseline and three months. Results revealed that the Tamoxifen merely intervention group had a statistically important lessening in the TC lipid parametric quantity ( p value A ; lt ; 0.05 ) , while the Anastrozole merely intervention group had an addition in TC lipid parametric quantity that was non statistically important ; nevertheless, the difference between the two groups was important. The co mbination group consequences showed a important lessening in TC ( P value A ; lt ; 0.05 ) , nevertheless the between groups differences were non important. A statistically important addition in HDL from baseline was noted overtime in all intervention groups ( P A ; lt ; 0.05 ) , nevertheless the difference between the groups was non important. Writers suggest that, although there was a little addition in TC in the Anastrozole merely group, this negative consequence was counterbalanced with the positive consequence of the addition of HDL in the Anastrozole group, and that there is no damaging consequence on the lipid profile when utilizing the AI, Anastrozole.19 Measurements were merely taken over a 3 month clip period, therefore consequences are limited and the effects seen may non prolong through longer intervention tests. This addition in HDL in the AI intervention group is contrary to the consequences seen in antecedently discussed surveies. Different AIs were used in each test and this unsimilarity in methods could account for the differences. Studies reexamining the disparities between AIs are necessary to find their several effects on lipid profiles and to measure if an AI is more good or damaging than the others. Comparison between Aromatase Inhibitors It is of import to understand the differences between each aromatase inhibitors several effects on lipid profiles to assist healthcare practicians choose the appropriate drug regimen for each single patient. In a multi-centre, unfastened, randomized survey, McCloskey et al5 compared the effects of Anastrozole, Letrozole, and Exemestane on lipid profiles in one hundred and two postmenopausal adult females, and randomized them into one of three intervention groups: Anastrozole ( 1 milligrams daily ) , Letrozole ( 2.5 milligrams daily ) , or Exemestane ( 25 milligrams daily ) , for 24 hebdomads with a 12 hebdomad follow up period. Measurements of lipid biomarkers ( TC, TRG, LDL, HDL, LDL/HDL ratio, Apolipoprotein B/Apolipoprotein A-1 ratio ) were taken at baseline and at the 12th, 24th, and 36th hebdomad. Consequences revealed that Exemestane had a important lessening from baseline in TC, nevertheless the differences between the three intervention groups were non statistically important ( p value=0.535 ) . The LDL/HDL ratio parametric quantity was significantly different for all three groups at the 12th and 24th hebdomad measuring, with Exemestane giving the greatest alteration ( p=0.007 ) compared to Letrozole ( p=0.025 ) and Anastrozole ( p=0.045 ) . This increased ratio in the Exemestane intervention group was due to the statistically important lessening in HDL ( p value A ; lt ; 0.001 ) . The TRG measuring for all groups showed much variableness, with Letrozole demoing a statistical important addition at 12 hebdomads ( p=0.011 ) versus the other AIs. This alteration from baseline did non last through the 24 hebdomad measurement period. No other alterations were noted between the three intervention groups. Writers suggested that those treated with Exemestane have an addition in hazard of inauspicious effects on the ratios finding atherogenesis.5 The lessening in the HDL parametric quantity in patients utilizing Exemestane is in understanding with the anteceden tly mentioned surveies that used Exemestane as an AI comparator of pick. Since Tamoxifen was non a confounding factor here, the suggestion that Exemestane perchance adversely effects HDL, now becomes a more significant and valid statement because the consequence is still seen without Tamoxifen act uponing the consequence. However, it must be considered that this survey used healthy postmenopausal adult females, non breast malignant neoplastic disease patients, as the sample population evaluated, and the consequences can non be imposed as the same consequences that might hold occurred if the population had used a sample of postmenopausal adult females with chest malignant neoplastic disease. Long clinical surveies utilizing the right population sample and sample size should be conducted to further understand the impact of each AI on the postmenopausal chest malignant neoplastic disease patient. This is one of the lone surveies available measuring the inauspicious effects of each part icular AI compared to one another. More surveies are necessary to corroborate the consequence that Exemestane offers more inauspicious hazard compared to Letrozole and Anastrozole. Decision Tamoxifen has been in usage for more than 30 old ages, and was considered the gilded criterion hormone therapy for handling postmenopausal adult females with endocrine dependent chest cancer.15, 20 Large epidemiologic surveies have shown that AIs are more efficacious than Tamoxifen in overall and disease free endurance rates, and hence are now recommended as first line accessory hormone therapy for postmenopausal adult females with chest cancer.3,15 With their known mechanism of action of striping postmenopausal adult females of serum estrogens, therefore taking estrogens protective effects on these cardiovascular hazard factors,6, 11 there is concern that AIs may hold inauspicious effects on lipid profiles. Most writers concluded that aromatase inhibitors have minimum effects or no inauspicious effects on lipid profiles in postmenopausal adult females with chest malignant neoplastic disease. However, it is hard to measure the true consequence of AIs on lipid profiles with Tamoxifen as the comparator since it has proved benefit on some lipid parameters,14 and because of the many different design methods used. Small sample sizes were restrictions in a few surveies ; therefore, the tendencies yielded in those tests may non be genuinely declarative of postmenopausal adult females with chest malignant neoplastic disease. Long term prospective surveies utilizing big sample sizes and patients with no exposure to any other hormone intervention besides AI, are needed to accurately measure if inauspicious effects on lipid profiles exist from the usage of AIs. From the current available information, though minimally, HDL is the parametric quantity most adversely affected by the usage of AI. This may be a cause of concern for some practicians since lessenings in go arounding sums of HDL are linked with additions in cardiovascular disease.15 Since HDL is considered good cholesterin and a positive hazard factor, diminishing the sum available in blood could perchance hold damaging effects on CVD. Healthcare practicians should be cognizant of this possible hazard of diminishing HDL with AI usage so that proper monitoring in their patients may be performed. Given that a current intervention option still includes the usage of Tamoxifen followed by exchanging to an AI, it is particularly of import to supervise lip id profiles since some studies14, 15, 17 have shown unfavourable effects on lipid profiles when doing this switch. To find if an existent hurt on CVD hazard factors occurs in adult females taking the non steroidal and steroidal aromatase inhibitors, more long term clinical tests should be conducted. In decision, aromatase inhibitors are being used more and more as first line accessory intervention in postmenopausal adult females with chest malignant neoplastic disease. Though it depletes estrogen beginnings, surveies show no well damaging effects on lipid profiles, with most merely demoing minimum, if any, inauspicious consequence. Placebo controlled surveies utilizing equal patient populations and sample sizes for appropriate sums of clip, are necessary to accurately depict the hazards of AIs on cardiovascular hazard factors. Healthcare practicians should go on to supervise lipid profiles in postmenopausal adult females with chest malignant neoplastic disease and develop individualized intervention programs utilizing current recommendations. Specific safety steps for patients utilizing AIs are non necessary,16 and the effects seen in the surveies mentioned in this reappraisal suggest that long term monitoring of all lipid parametric quantities should be a portion of the postmen opausal adult female with chest malignant neoplastic diseases intervention program. Surveillance of hazard factors overtime in these adult females with should assist forestall unfavourable cardiac events. How to cite Lipid Profiles In Postmenopausal Women Health And Social Care Essay, Essay examples

Cumberland Metal Industries free essay sample

The table below breaks down the economic value in use of the CMI pads according to both the Colerick and Fazio tests. I used the data from each case to derive the number of hours of driving required to complete the job with both the asbestos and CMI pads. The difference in time to complete the job multiplied by the cost per real hours was one part of the economic value in use. The economic value that is created by use of the CMI pads is different in total dollars between the Colerick and Fazio tests. However, when you divide those values by the number of feet driven in each test you derive the same economic value in use of $0. 46/ft. When you examine the breakdown of savings associated with a decrease in project time between the 2 tests you find that the Colerick test had a saving of $. 0/ft, and Fazio $. In the current state the pads are a commodity product manufactured by several small firms. The fragmentation of the distribution channel combined with the commodity nature of the product has put most of the channel power in the hands of the equipment distributors who despite carrying the products mostly as a matter of necessity are still enjoying a 30-40% gross margin on the sale of the pads. CMI is in the situation where they can circumvent the channel and provide their product direct to the market. CMI is able to offer their product direct to the market because they have a very specific consumer target engineering/construction contractors, and independent pile-driving contractors. It would be easier to create awareness among these consumers by direct sales than trying to have the various outlets that exist in the conventional channel do so. This also allows CMI to avoid the situation of having their distribution limited by the number of outlets that they can get to carry their product. If CMI is able to gain a monopoly in the market then they can approach distribution through the conventional outlets because they will have a strong brand and will be able to put pressure on distributors to accept a lower price. The nature of the CMI pads makes them much longer lasting than the asbestos pads. Thus one assumes that CMI would be looking for a high EBIT on this product rather than ATR. By circumventing the distributors they are able to capture more of the Total Channel Margin and increase their EBIT. Segmentation of the market can be done by applying the variables of willingness to pay, benefit, and the heavy half or 80 / 20 rule. Willingness to pay is appropriate but needs to be approached in an abstract way. There are many contractors in the pile driving business that are looking to maximize their take, of these some are not sophisticated enough, or their business is not large enough to realize substantial gains on the time savings through use of the new pads. They are going to be your smaller independent construction contractors and pile driving operations. They will typically see the lower price of the asbestos pads and choose them. You can also look at willingness to pay in another way the more sophisticated outfits will realize that by paying more for the CMI pads they will realize savings on time and cost on their projects over all. The players in this segment are likely to be the larger international construction contractors like Conmaco and Raymond International, as well as larger independent pile driving firms. The market can be segmented by benefit because there are those consumers or purchase influencers who look at the impact the pads can have from an engineering standpoint. Because CMI pads transfer the energy from the pile more efficiently they were less likely to result in damage to the pile that may affect the integrity of the foundation. The players that would be in this segment would be the architectural and consulting groups, as well as the more sophisticated of the larger engineering/construction contractors. There is a second benefit segment that you can identify as well. This group would be defined by there need or want for a safer work environment. The use of asbestos pads would be undesirable to this segment, and would be more likely to choose the CMI pads. This segment would be harder to identify because they would be spread out amongst the different size firms. It is likely that at the time of the case larger firms were not yet concerned about the major litigation issues surrounding the use of asbestos. Since it is most likely site workers that would be identified in this segment’ it is likely that smaller firms were the principle is on site at the projects would be the major part of the segment. The last segment would be the heavy half. This is appropriate b/c there is likely to be a small number of larger firms that handle multiple pile driving project at a time, as well as the larger ones. It is then logical to ssume they are going to consume a majority of the pads in the market. This segment is likely to consist of a few of the larger engineering/construction firms. When looking to price the CMI pads they would first need to look at the equivalent cost of the asbestos pads. Using the total number of sets used between both tests (70) and the total number of feet driven (27000) you get and average of 386 ft per set. Given the conse rvative estimate of the CMI set of pads having a durable life of 10,000 we can calculate that you would use 26 sets of asbestos pads over the durable life of one set of CMI pads. Multiplying that figure by and average price of $45/set you get $1170, providing a good base. But this would put them at 24% margin per pad if using current equipment and 55% after retooling(retooling adds $16. 7/pad to total manufacturing cost), without adding extra capacity over 250 pads per month. If they choose not to retool they would have increase their price, they have room to do so because they are creating project cost savings at an average of $. 35/ft or $3,500 per set of pads. If they increased their price to $1800/set or $300/pad they would be realizing 50% margins per pad without retooling, and 71% after retooling. They would also be providing about $2,900 in project cost savings to the consumer. CMI should distribute these directly to the consumer for the reasons mentioned earlier in this analysis. There key segment should be the heavy half users consisting of the larger engineering and construction firms. They should also focus on the benefit segment of Architectural/Consulting engineers who can drive demand for the new pads. Key to gaining this segment would be a favorable review by Dr. McCormack. The NATRU listed bellow estimates the volume of pads that should be produced in each of the first five years. I used a rough estimate on the number of pile hammers existing in the market of 22,750. This number was then decreased in each of the five years by the number of trial from the previous year. This assumes that the market is not growing and that non repeat customers will not trial the product again. The steady state volumes of repeat customers are captured in the total of each year. Because there is a lot of uncertainty about how to gain awareness of the new product in the market I kept awareness very low at 15% in the first year increasing of the next five to 55%. Much of the growth in awareness would be contributed to extended time in the market of and active sales force and word of mouth amongst market players. I assumed a moderate amount of trial given the evidence available about the superiority of the pads. This rate would increase over time as well because there would be more evidence based information available to the market. Because the pads are somewhat of an experience good, and all evidence points ot a favorable experience I weighted the repeat rate heavily at 80%.

Impact of Maintenance Activities on the Environment Essay Example

Impact of Maintenance Activities on the Environment Essay The Academy Graduate Studies, Benghazi. Term Paper for Maintenance Management Course Titled: Impact of Maintenance Activities on the Environment. Prepared By: Haitham Hashem 4657. Farage Shem 4465. Supervised By: Prof. Dr. Farage Elfeituri. Contents Introduction3 How Can Maintenance Affect the Environment? 4 Limitation of Environmental impact in maintenance operations4 I. Evaluation of Environmental aspects in maintenance4 II. Environmental aspects to be considered5 1. Procurement Concerns5 . Hazardous Materials Storage6 3. Operating Practices6 4. Washing Activities7 5. Reuse and Recycling8 6. Painting Operations9 III. Definition of appropriate actions to limit significant environmental aspects / impacts10 The conclusion12 References13 Introduction When evaluating the overall environmental impact of a product throughout its life cycle, careful consideration shall be given to the duration of the life cycle as well as to each of the life cycle phases. The relative importance f the impa ct of each life cycle phase may in fact be significantly different for a short life cycle product compared to a long life cycle product, the following table shows relative importance of life cycle phases on the overall environmental performance of a product: | Procurement| Design| Manufacturing| Use | Maintenance| End of life| SLC| ***| ***| ***| ***| **| *| LLS| ***| ***| *| ***| **| *| | | | | * Not very important| ** Important| ***Very important| For a long life cycle product, it is obvious that the impact of in-service use as well as maintenance of the product will be of significant importance. For example, a lack of maintenance for a vehicle or a machine may lead to a significant increase in the consumption of fuel or other consumables required for proper timing. Particular attention shall therefore also be paid to educating consumers or users to ensure the product is operated in the most appropriate and environmentally friendly condition, and in particular to ensure it is in line with applicable standards or regulations and in accordance with the initial characteristic of the product as delivered. How Can Maintenance Affect the Environment? Maintenance activities can generate a variety of solid and hazardous wastes. Commonly generated wastes include out-of-date supplies, wastewater, oils, petroleum products and greases, solvents (both waste liquids and vapors), paints, and consumed components (seals, belts, bearings,†¦), as well as waste metal, cardboard, and paper. Each of these wastes has the potential to negatively affect one or more of the environmental media (i. e. , land, water, and air), in addition it these activities it can also generate a considerable amount noise which is a kind of pollution. We will write a custom essay sample on Impact of Maintenance Activities on the Environment specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Impact of Maintenance Activities on the Environment specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Impact of Maintenance Activities on the Environment specifically for you FOR ONLY $16.38 $13.9/page Hire Writer However, such activities and practices as segregating wastes, using proper inventory control, preventing spills, practicing preventive maintenance, improving process efficiency, and recycling can help minimize these impacts. Limitation of Environmental impact in maintenance operations When engaged in a environmental complain, either to improve a maintenance system or designing a new one, the following considerations should be toke into account: I. Evaluation of Environmental aspects in maintenance To limit environmental impact of maintenance during the use phase of the asset, it is essential for the various environmental aspects of the asset to be identified as a prerequisite. This can be done according to the methodology defined in any Environmental Analysis input/output box method, this analysis shall also identify which of the various regulatory frameworks should be applied when maintaining a product, as well as other commitments or company policies to be complied with: The result of this streamlined analysis shall be improved knowledge and identification of the significant environmental impacts related to maintenance operations. Analysis and optimization of the preventive maintenance (PM) program for equipment items associated with the organization’s significant environmental aspects will be necessary to make sure that maintenance is adequately planned, additionally, how are potentially significant environmental impacts addressed in the job plans for PM activities? There are two starting points for this optimization: Either examine existing PM activities as they come due and modify them to take into account the analysis of environmental aspects, or begin with a list of the organizations significant environmental aspects, check for appropriate PM coverage, and set up PM actions as needed. Predictive maintenance (PdM) activities are of several types: vibration, lube sampling, infrared scanning, etc. PdM actions are focused on more critical equipment and this proactive approach may be well suited for equipment associated with the organizations significant environmental aspects, looking into the PdM program can take the same two starting points as in the PM program above. As for corrective maintenance (CM), it doesn’t distinguish from PM and PdM so much, except for the fact that waste management becomes a focal point, due to the unpreventable association of waste generation to CM operations. II. Environmental aspects to be considered 1. Procurement Concerns Purchasing decisions are an important element of pollution prevention. Making environmentally sound purchasing decisions can help reduce the amount of waste generated by a vehicle maintenance shop. In addition, the purchasing of recycled content products helps support markets for materials collected for recycling. Will the facility use recycled automotive maintenance products and retread tires? Such products as refiltered or re-refined oil and hydraulic fluids, as well as recycled antifreeze and solvent, are available for use in vehicle maintenance operations. Will the facility identify and use the least toxic product available to complete a job? Many maintenance products are formulated with high percentages of volatile organic compounds (VOCs) and toxic constituents. Safer, more environmentally sound materials are, however, available and perform as well as traditional products. For example, non-chlorinated solvents can be substituted for chlorinated solvents, detergent-based solutions can be substituted for caustic solutions in many applications, and water-based cleaners often can be used instead of organic solvents. Will long-lasting or synthetic oils be used when possible? Long-lasting oils reduce waste generation because they do not need to be replaced as often. 2. Hazardous Materials Storage Maintenance operations often involve the use of hazardous materials. The use of these materials can affect the environment through improper storage, air emissions of volatile chemicals, and spills and other uncontrolled releases, as well as the potential generation of toxic waste materials. Will hazardous materials be properly stored and handled? Proper storage and handling can include labeling containers, protecting materials from the elements, maintaining secondary containment, ensuring the compatibility of stored materials to avoid explosion hazards, and following instructions on the products Material Safety Data Sheets (MSDSs). Will the access to hazardous materials be limited? Limiting the access to hazardous materials allows a shop to keep track of chemical usage more easily and helps reduce unnecessary waste generation. Will a first-in, first-out inventory control system be used? This type of system helps prevent materials from expiring prior to use and becoming unnecessary waste. Efforts should also be made to minimize inventory levels by purchasing only the amount of material that will be needed in a reasonably short period of time (e. g. , 30 days) to reduce loss from spoilage. At the same time, however, materials should be purchased in the largest containers appropriate to minimize excessive packaging. 3. Operating Practices The use of oils, solvents, and other maintenance products can have significant effects on human health and the environment. The adoption of environmentally conscious operating practices can, however, reduce these impacts. Will maintenance bays be located to minimize the potential impacts of maintenance activities on the surrounding environment? Will the facility avoid unnecessary maintenance? One of the biggest sources of waste generated from maintenance shops comes from unneeded maintenance activities. An example of a way to minimize this waste is to change equipments’ fluids on an as-needed basis rather than according to a fixed maintenance schedule not based on equipment usage. Does the facility operating plan specify reducing the number and types of products, such as solvent, that will be used at the shop? Minimizing the types of different solvents used can simplify inventory procedures, reduce waste management issues, and facilitate recycling. Does the facility keep copies of its spill control and countermeasure plan for hazardous materials in each shop? Will the facility use drip pans, secondary containment, and other collection devices to help reduce the impact of spills and the use of absorbent products? Will a bulk fluids distribution system be cost effective? This type of system allows employees to dispense only as much product as is necessary for a job, in addition to reducing the potential for spills associated with the use of large, unwieldy containers. Will the facilitys solvent sink be operated to reduce environmental impacts? Environmentally preferable operating practices include pre-rinsing parts with dirty solvent before using fresh solvent to extend solvent life, removing parts from the sink slowly to reduce solvent dragout, using drip racks to reduce solvent loss, keeping sink lids closed when not in use to minimize the evaporation of solvent, not leaving solvent streams running, and cleaning out sludges regularly to maintain fresh solvent. 4. Washing Activities Washing can generate a large quantity of wastewater that may be contaminated with oils, greases, and dirt, as well as washing soaps and detergents. In some States, it is illegal to wash equipments without wastewater recycling equipment under certain conditions. Does equipments washing need to take place onsite? In some instances, offsite washing is a more efficient and environmentally preferable option. However, if properly implemented, onsite washing can be preferable since it can reduce the amount of fuel used expressly for moving the equipment for washing. Will equipment washing take place at a centralized, enclosed, and contained area to reduce potential impacts to the surrounding environment from runoff? Will equipment washing be conducted on an as-needed basis, rather than according to a fixed schedule? Reducing unnecessary washing can significantly reduce wastewater generation. Will the wastewater from the wash racks floor drains be properly treated onsite (e. g. , by removing oils, greases, and other contaminants) prior to discharge to a waterbody? Will an oil/water separator be used? Will the wash rack use detergents that do not contain phosphates or toxics? Can water from the wash rack be captured, filtered, and reused rather than being released? If a facility will maintain a large number equipments that require washing, a custom designed washing facility may be cost effective. If equipments washing must be performed by hand, a high volume, low pressure washer system will be more cost effective than a simple hose in terms of reduced personnel hours and energy usage. 5. Reuse and Recycling Many of the waste materials generated during vehicle maintenance activities can be reused or recycled into usable products. Reuse and recycling are preferable to treatment and disposal because they remove materials that would otherwise become waste. Are there plans for adequate segregation and containment of waste oil, antifreeze, and solvent? Each of these materials can be reclaimed or recycled if segregated. However, commingling these wastes makes recovery more difficult or impossible and dramatically increases waste disposal costs. Will the facility use solvent or antifreeze reclamation units? The onsite recycling of fluids is often a cost-effective pollution prevention option for larger shops. When onsite recycling is not cost effective, these materials can be segregated and picked up by a contractor for offsite recycling. Will the facility collect scrap metals generated at the shop (e. g. , used parts, empty material storage drums) for recycling? In some instances, punctured aerosol spray cans and drained oil filter casings may also be recycled as scrap. Will automotive batteries be collected and stored for recycling? Will the facility reuse cardboard and other packaging received in the delivery of parts and materials or collect it for recycling? 6. Painting Operations Wastes associated with painting operations include unused paints and dirty thinner. Thinners and solvents can also be sources of volatile organic compounds VOC emissions. Used spray booth filters are also waste products that may be generated from these shops. Proper training of employees and the use of high efficiency equipment can help reduce waste generation. Can water-based coatings be used instead of solvent-based coatings? some industries are working closely with paint manufacturers to develop acceptable substitutes for solvent-based paints. Will the facility use high efficiency painting technologies? When properly used, high volume, low pressure (HVLP) and electrostatic painting systems can reduce the amount of paint needed for a job and the amount of VOCs released to the air. Will employees be trained to use as little solvent/thinner as possible to clean up after painting activities? Will the facility employ a gun cleaning station? Gun cleaning stations capture the thinner/solvent shot through the gun and condense it for reuse instead of venting the substance to the air. In some cases, it may be possible to use water-based gun cleaners as an alternative to solvent thinner. Will the paint shop utilize reusable polystyrene booth filters? Traditional paint booth filters often must be handled as hazardous waste because of the presence of wet paint or paint containing lead or chromium. Polystyrene filters can be cleaned with compressed air and reused (with the paint residue captured for disposal). Once it can no longer be used, the cleaned filter often can be disposed of by dissolving it in a waste thinner drum. Will painting operations be located in an enclosed and properly ventilated area to reduce potential environmental releases? Will employees be trained to minimize the amount of waste paint generated by mixing only the amount of paint needed for a job? III. Definition of appropriate actions to limit significant environmental spects / impacts Appropriate limitation of environmental aspects in maintenance operations shall be performed in several ways: By considering the life cycle at the earliest stage, appropriate check lists shall generally be useful to ensure efficient and effective limitation of the environmental impact through appropriate control of emissions and/or exposures. Through appropriate training and education of maintenance operators and users, in this case, proper documentation as well as operator qualification and user awareness will be fundamental. Including careful selection of external services with respect to environmental requirements. Appropriate objectives and targets shall be defined in the context of a life-cycle oriented Environmental Management System, and associated action shall be identified and conducted through an Environmental Management Programme for Maintenance operations. The efficiency of the actions set up to limit overall environmental impacts in maintenance operations shall be regularly reviewed. Any deviations shall be monitored and corrected through corrective or preventive measures. Also Pollution Prevention/Reduction Environmental Impact Training in maintenance shops is closely linked with employee attitudes toward their work and the environment. A facility that provides basic environmental awareness/pollution prevention training and enthusiastically supports pollution prevention on a daily basis will have a noticeable effect on worker attitudes and can help reduce vehicle maintenance waste streams through such procedures as good housekeeping, spill prevention, and improved materials handling. The following pointes provide examples of actions to be performed to limit the environmental impact: * Identify all operations demanding energy, water or other resources, and the relevant requirements (environmental analysis). Identify all applicable regulatory frameworks to be complied with where the operations are performed. * Identify all consumables used and the relevant Hazards. Collect all MSDS (Material Safety Data Sheet) and data and have them available. * Select consumables to be recommended for maintenance operations with respect to environmental and health / safety Hazards. * Provide appropriate training for users when necess ary. * Ensure regular checks are made with respect to the initial performance of the products and proceed with appropriate repair, if necessary. * Identify any materials required to limit spillages, leaks, emissions, etc. nd the corresponding damage to the environment, and keep these materials available for this purpose, particularly in abnormal situations. * Select operators (including external services) on the basis of environmental requirements and give them appropriate training and inform them that the protection equipment is specified on the MSDS. The conclusion The maintenance activities could have significant adverse outcome on environment if not managed properly, although most of these negative effects can be prevented or reduced in cost-effective manners if addressed properly. The environmental management of maintenance operation, through the implement of environmentally sound policies, considering the environmental impact of the equipments life-cycle related to maintenance prior to purchase, and adopting environmental friendly practices in maintenance operations including waste management, will considerably improve the environmental impact of maintenance activities. The maintenance planning and scheduling functions will be expected to add environmental management activities to their agenda. Several questions worthy of investigation arise: How is the backlog sorted to identify overdue preventive maintenance work? How do activities associated with significant environmental aspects rank in the organizations prioritization process? What Key Performance Indicators are in place for assessing whether the organization is complying with its operational controls and achieving its objectives for environmental performance? Are supervisors clearly responsible for seeing that environmental management activities are performed on time? The CMMS is a great tool for tracking environmental compliance. Adding an equipment classification for those items associated with significant environmental aspects is an obvious change to make. There may well be new equipment items to include in the hierarchy. Work order types also may be appropriate for an additional type. Designing environmental performance reports is a good action. A responsive CMMS that is consistent, reliable, timely, and accessible will be a super aid for maintenance environmental management. Although these changes in maintenance practices may seem time-consuming at first, they do not all need to be implemented at once. A good plan of attack can incorporate these changes in an orderly and cost-effective manner.

English family Essay Example

English family Essay Example English family Essay English family Essay As soon as the advert starts there is an instant drumbeat. It reminds me of a beating heart or as if an important announcement is about to be made. When the ad first starts you only see a horse treading in the water and then you instantly think what is going on here? The voice over says Ahab says I dont care who you are, heres to your dream. We then see the men entering the sea to catch this wave. Meanwhile the drumbeat is still going on.Next we see a man pouring a pint of Guinness. The voice over then says Heres to you Ahab. The first drum hits the beat withal his heart. Then we get back to the wave and you can see the horses in the waves clearly. Now you know why a horse was treading water earlier in the advert. We then stay with the men surfing this 40 ft wave. You can see the fear in eyes of the man. The men then run onto the beach satisfied in what they have achieved. Then the voice over says, Heres to waiting. The slogan appears with a pint of Guinness. This advert will always be memorable to me just because of its originality and because it is symbolic, but if nothing else is memorable in the advert, the drumbeat is.Other adverts become mini soaps and each advert is like an episode. The Oxo adverts were like this. The Oxo ads reflected society at the time. It was the wife making dinner for the husband to keep him happy. At the time the Oxo adverts were subliminal, it advertised the women who used Oxo would keep the family happy. They tried to make it up market by using people with posh accents.The same people were used in each advert and it was like a new member of the family is introduced in each ad or episode. When the new family was introduced in 1983 they were more up to date, more with the time. Although it still showed the woman of the family cooking it was not to keep the husband happy. It was in the early eighties when women became more powerful. Everything had changed for the better. The product was directed at housewives and maybe thats why the adverts were pulled in 1999, because society was not like that anymore and some women would be annoyed to see this.If you wanted to know what a real English family was like this was the perfect family. They were so real people thought they actually were a real family but they werent. This is why the Oxo family were so memorable. The Nescafe adverts starte in 1987 and were more glamorised than the Oxo family yet they were also subliminal. The people in the ads were more glamorised and business like. Every advert was like a new episode. The people started off by meeting at work and eventually became a full-blown affair over many episodes. The message was if you drank Nescafe you would be like the middle class people that were in the adverts. Most of the ads advertised a dinner party lifestyle scenario. It was an ongoing romance.Yet these were not the first ads of its sort. The Cointreau ads presided the Nescafe ads. The Cointreau ads were the first adverts to have an ongoing romance. The first advert, which was released in 1974, was very glossy and false. The ad consisted of a French man explaining the contents of Cointreau to a woman who is hanging on his every word. Cointreau is a liqueur so you can equate the product to the lifestyle. If you have seen the Cointreau adverts you can see where the Nescafe adverts came from. These were memorable because they were the first of its sort they were the originals.Other adverts are on TV most of the time but my next advert is seasonal and only appears on our screen sat Christmas. These are the Famous Grouse adverts. The adverts consist of a bird doing something for ten to twenty seconds. The adverts only appear at Christmas because it is the key time for gifting opportunities. The type of person that would drink Famous Grouse is likely to kick their shoes off and relax in front of a log fire.The adverts consist of a bird doing something that you would never see another bird do, for example ice skating or tap dancing which is then followed by the pun line which separates it from other whisky ads. These adverts are memorable because they use animatronics in a very clever way; the bird does something totally unrealistic. My final advert is not on television. It was shocking for people and had to be seen everywhere. It is the opium adverts starring Sophie Dahl. Some people said the advert was very offensive yet women did not complain when the advert was in womens magazines. This is because in magazines they have the choice to look at the advert or not and was directed at a specific audience. 700 people complained about the advert.It was deemed sexually suggestive and degrading to women. It is not the fact that Sophie Dahl is naked in the advert. It is the pose she is in; she is saying Give it to me. People say the advert is a danger to drivers and children should not have to go to school and see that on a billboard when they go to play in the playground. Some people even thought the advert suggested rape. In Bradford the words We are not for sale. This is a rape fantasy. Were sprayed on the poster.At first the advert was seen as too sexy yet a few days later it was described as Beautiful, beguiling and photographic art.. It has been said that pictures of skinny clothed models promoting anorexia and bulimia are far more vulgar than seeing Sophie Dahls healthy size 14 body. Many reviews in papers prove this. Myself I do not find this advert offensive yet it is not right that it is on billboards directly outside primary schools. The children would mature too fast and would not have fun like they should be at that age. I can also see why people could see the advert suggesting rape as the pose Sophie Dahl is in is very passionate and does suggest sex.The advert is memorable because of the amount of complaints it received. Some companies will even make an advert outrageous on purpose to get publicity, so that the advert and more so the product will be memorable. Basically adverts are memorable for many different reasons. It may be because they are funny or because they are unique in their own special way but just because an advert is memorable it does not mean that the product is. So next time, when you watch an advert just think if you will remember it, when you are older.

Mental health case analysis Assignment Example | Topics and Well Written Essays - 2500 words

Mental health case analysis - Assignment Example .......................................8 Signs..........................................................................................................8 Formulation of Intervention Strategy....................................................................9 Implementation and Interprofessional Elements of the Treatment.......................10 Evaluation and Monitoring of Solutions...............................................................11 Conclusion............................................................................................................12 References.............................................................................................................13 Appendix 1............................................................................................................15 Introduction This paper is based on a mental health scenario involving a patient, Kathy. In the scenario, it is apparent that Kathy is going through a mental health crises that has c aused her to resort to the following circumstances: 1. Disruptions in her family life 2. Disruptions in her work life 3. Emotional problems 4. Alcohol abuse 5. Social isolationism. These issues culminated after a series of incidents that occurred to her. She recently lost her mother and prior to her passing, she could not reconcile her differences with her. Due to this, she died without them making any substantial peace. This led to a serious depression which has created the effects listed in 1 to 5 above. This research attempts to diagnose Kathy's problems and prescribe a solution to it based on the framework of public health and mental health. In doing this, the following objectives will be addressed: 1. A critical review of literature relating to public health and mental health relevant to the issues at hand. 2. A discussion on how to diagnose and assess Kathy's problem based on the principles of mental and public health. 3. Formulation of a strategy to help Kathy to overcome her challenges. 4. Evaluation of the strategy and the interprofessional elements involved in solving Kathy's problems. Public Health and Mental Health as a Tool to the Issues The definition of the scope of mental health is not very simple (Simpson, 2009 p3). This is because mental health is something that comes as an abstract form of medical conditions. Its scope spans from behavioural disorders to mental functions as well as other emotional conditions (Tengland, 2001 p1). Due to this, it typically involves the work of numerous health professionals and has always been a kind of 'joint' discipline with numerous players. The responsibility for mental health and in a public health context revolves around psychologists, physicians/nurses/hospital staff and sociologists. Sociologists might be interested in the effect of a mental health situation on the wider society. The case under review, it is apparent that the mental health challenges of Kathy is affecting not only her as an individual, but her immediate family: her children, husband and her work as well as the wider society. As such, mental health is an issue that concerns sociologists and they have an interest in studying it to identify its scope and effect in order to provide the best framework to contain it. Psychologists have the technical responsibility of dealing with mental health cases. They have to tools and resources necessary to diagnose and deal with the mental related cases. Additionally, doctors often deal with complications related to mental health

Understanding Organisation Development Essay Example | Topics and Well Written Essays - 1000 words

Understanding Organisation Development - Essay Example Organization Development (OD) is a planned effort to increase the overall effectiveness of an organization by changing the existing beliefs, attitudes, values, and structure of the organizations. It is not possible for an organization to stick with the conventional methods in a world which undergoes rapid changes, literally in every second. This paper briefly explains the importance of organization development in a changing world. There are no organized or standard definitions for organization Development because of the vast areas it covers. ODportal.com defined organization development as changing people and organizations for positive growth (ODportal.com, n. d). Gallos defined OD as an effort; planned, organization- wide, and managed from the top to increase organization effectiveness and health through planned interventions in the organization’s process using behavioural science knowledge (Gallos, 2006, p.1). People or the workforce is the backbone of every organization. Even though other resources like materials, machines and money are important for an organization, all these resources are controlled by the manpower and the importance of manpower cannot be underestimated in development of an organization. People or the workforce is undergoing constant changes every day. The requirement of the current generation is different from that of ancient generation. Science and technology has developed a lot and the life styles and the living standards were also changed a lot. Based on the changing workforce and changing customers or consumers, organizational principles also need changes. Organizational culture, climate, attitude, behaviour, structure etc need to be changed or updated in order to meet the demands of the changing world. OD is the only option available for organizations to accomplish this task. â€Å"Organizational Development (OD) is all about managing change† (Devalt, 2008). â€Å"As our children growing up, we used the tool of OD in our parenting†

Business Arrangements & Global Business Law Coursework

Business Arrangements & Global Business Law - Coursework Example The main advantage is that there would be more than one headcount to take care of the work. Since there are more than one the cost of running would get equally divided and more capital would be available. The income split will make the tax liability less for each of the partners. The business affairs would be private and there would be limited regulations from the external sources (MacIntyre, 2007). It would be easy to change the legal structures with the changing circumstances. Along with the advantages, there are disadvantages as well if they run it in the current model of operation. The liability of debts for each partner might become unlimited. Since there is no written document of the partnership past two years there might be cha ance of friction between the partners. If Barbara, Helen, and Maureen have a written document with all the valid points of their partnership it would be easy for them to avoid any kind of confusion in the future, which might lead to conflict in partners hip. As they are going to expand their business and employee, two people, it is advised to have everything in writing. Task 2 When Barbara, Helen, and Maureen are planning to make their business a limited liability company or LLC it is necessary for them to know about various types of LLCs (GCSE Business Studies, 2004).

Skills for Intercultural Communication

Skills for Intercultural Communication Introduction: Culture can be defined as the quality in an individual or society that emerges from a sympathy toward what is viewed as astounding in expressions, letters, behaviour, insightful interests, and so forth while the communication is described as the conferring or trading of data by talking, composition, or utilizing some other medium. Intercultural communication is a type of correspondence that means to impart data crosswise over diverse societies and cultural gatherings. It is used to show the extensive variety of correspondence courses of action and issues that rise-up in an association made up of people from diverse religious, social, ethnic, and belonging from distinct educational backgrounds. Body: The essential skills of intercultural communication are in a far-reaching way general communication abilities that might be utilized all around by all societies and races. These skills are basically tweaked in a course that looks into the cultural constraints. A simple idea as an example of such communication abilities in the intercultural environment is to listen without judging, rehash what you comprehend, affirm implications, give proposals and recognize a shared comprehension (Kwintessential.co.uk, 2014). In doing vast research, numerous researchers have recognized different fields and themes they consider critical for study in the field of intercultural communication. A few researchers (e.g., Gudykunst, 1987; Rich, 1974; Stewart, 1978) set a general research scope for the study while others (e.g., Hu, 2004; Jia, 1997; Watchman, 1990; Samovar, Doorman, Stefani, 2000) accept the more particular variables ought to be inspected in intercultural communication research. The general contents for doing research are made by Rich (1974). He discussed that the contents of intercultural communication might be arranged into five structures: intercultural communication, global communication, interracial communication, between ethnic or minority communication, and contractual communication. Gudykunst (1987) keeps up that intercultural communication research ought to incorporate four classifications: intercultural communication, culturally diverse communication, universal communication and similar mass correspondence. Another researcher Stewart (1978) focuses out that the research of intercultural communication ought to deal in genuine circumstances hurdles faced by people belonging from different backgrounds, which pointed out to arrange training programs for creating sense of humanity b/w intercultural diversified people. He expresses that training for intercultural communication ought to lead the trainees through nine phases of progressive change, empowering them to see an alternate culture all the more in a detailed way. As discussed above some contents of intercultural communication some additional contents were also brought into consideration as some different researchers (e.g., Hu, 2004; Jia, 1997; Doorman, 1990; Samovar et al., 2000) think that the research on intercultural communication ought to manage more particular variables influencing the nature of intercultural communication. Watchman (1990) separated those variables into eight components: attitudes, social organization, patterns of thought, roles and role expectations, language, space, time, and nonverbal expression. Later, Samovar et al. (2000) categorized the eight components into four general associating gatherings: observation, verbal methods, nonverbal methodologies and context oriented components. It is on the grounds that all these components could be distinguished, dissected and classified that the exploration of intercultural communication can be led (Jia, 1997). In this manner, the principle concern of these researchers is to an alyse the components that may impact intercultural communication and attempt to decide how to uproot the obstructions faced during communication created by contrasts in dialect, sustenance, and dress, social cultural practices. In a pileup, regardless of what different researchers have made on the characterization of intercultural communication research contents, it is by and large concurred that the investigation of intercultural communication expects to comprehend the impact of society on our mentality, convictions and practices with a specific end goal to diminish misconceptions that come about because of social cultural varieties (Chen Starosta, 1997). To put it all the more basically, intercultural communication exploration ought to be concerned with the particular contents influencing genuine intercultural communication in genuine living, regardless of whether it is in regards to intercultural, culturally diverse, interracial or between ethnic correspondences. As to every individual component, there exist some marginally diverse perspectives on what precisely ought to be inspected. In this study, taking into account the genuine research of the gathered information, we receive the classification proposed by Hu (2005) as a kind of perspective to order the research contents of the gathered articles. In his study, Hu (2005) arranged the intercultural communication research contents into the accompanying five classifications: summary, theory and research methods, cultural comparison and contrast, intercultural adaptation and training, special topics. Among the five classes, some special and worth-noticing points refer to the articles that dont have a place with any of the other four classifications (Hu, 2010). People are doing communication since four million years. Then again, the conception of culture is assessed to have taken place around 35,000 years prior. Today, both society and communication have advanced significantly and have gotten to be related of each other, to the point that communication is thought to be a result of culture. Accordingly, our own particular culture has a profound effect on our considerations and practices. Since each one has its unique viewpoints, intercultural communication might be the reason for clash and issue. There are three principle issues which are at the foundation of the issue of intercultural miscommunication: dialect as an obstruction, social differences and ethnocentrism. We will discuss these three ideas in circumstances in which intercultural communication is usual, for example: the work environment, the classroom and entertaining trips. The way individuals communicate differs broadly between, and even inside, societies. One part of communication style is dialect use. Language has dependably been seen as a connection between individuals however it can additionally constitute a boundary. Crosswise over societies, a few words and expressions are utilized as a part of distinctive ways. Besides, correspondence between societies which dont have the same language is extensively more troublesome. Each one in a society has its unique language structure, interpretations and structure which causes complexity in intercultural communication. Case in point, in Asian nations the saying no is seldom utilized, with the goal that yea can signify no or maybe. Subsequently, an American flying out to Japan may be viewed as inconsiderate in the event that he disregards this standard. Besides, people who are not happy with a certain language may not be considered important (StudyMode, 2014). The issues in intercultural communication normally originate from problems in message transmission. In correspondence between individuals of the same society, the individual who gets the message deciphers it focused around qualities, convictions, and desires for conduct like those of the individual who sent the message. At the point when this happens, the way the message is deciphered by the beneficiary is liable to be reasonably like what the speaker planned. On the other hand, when the recipient of the message is an individual from a different society, the beneficiary uses data from his or her society to translate the message. The message that the collector deciphers may be altogether different from what the speaker proposed. Attribution is the methodology in which individuals search for a clarification of someone elses conduct. When somebody doesnt comprehend an alternate, he/she generally accuses the disarray for the others ineptitude, double dealing, or madness. Successful communication relies on the casual understandings among the gatherings included that are focused around the trust created between them. At the point when trust exists, there is verifiable seeing inside communication, social contrasts may be disregarded, and issues could be managed all the more effectively. The significance of trust and how it is created and conveyed differ crosswise over social orders. Also, a few societies have a more noteworthy inclination to be trusting than others. Nonverbal communication is conduct that uses without words however it regularly may join by words. Nonverbal correspondence has been indicated to record for somewhere around 65% and 93% of deciphered correspondence. Minor varieties in non-verbal communication, discourse rhythms, and dependability frequently cause doubt and misperception of the circumstances among culturally diverse gathering. In the 1980s Geert Hofstede found 5 major measurements of national cultures that might be seen to outline diverse values in distinctive national societies. These qualities may have outcomes for how individuals in diverse societies carry on, and how they will possibly act in a work related context. One of these qualities is independence vs. cooperation. In individualistic societies individuals are required to depict themselves as people, who look to fulfil singular objectives and needs. In collectivist societies, individuals have more prominent stress on the welfare of the whole gathering to which the individual has a place, where individual needs, needs and dreams are frequently situated aside for the benefit of everyone(Geert, 2001). Conclusion: Taking everything into account, it might be expressed that there are new and developing progressions going ahead in the field of interchanges coming about because of changing demographics of the groups in which the business society must work. An alternate energy, which is changing the way business correspondence behaviour of individuals, learning recovery and capacity and additionally the route in which societies are continuously directed, is the appearance of new evolved technologies. The expert communication environment ought to, be examined and has expected a far expanding level of importance in the present age(Anon, 1999). References: Kwintessential.co.uk, (2014).An Introduction to Intercultural Communication | articles | cultural services. [online] Available at: http://www.kwintessential.co.uk/cultural-services/articles/introduction-intercultural.html [Accessed 7 Sep. 2014]. Hu, Y. (2010).International Journal of Intercultural Relations, (35), pp. 555. StudyMode, (2014).Problems in Intercultural Communication by Study mode. [online] Available at: http://www.studymode.com/essays/Problems-In-Intercultural-Communication-25747.html [Accessed 7 Sep. 2014]. Geert, H. (2001).What are Geert Hofstedes 5 Cultural Dimensions?. [online] Businessmate.org. Available at: http://www.businessmate.org/Article.php?ArtikelId=4 [Accessed 7 Sep. 2014]. Anon, (1999).Appreciating the Diversity in Multicultural Communication Styles. [online] Available at: http://static.highbeam.com [Accessed 7 Sep. 2014]. Annotated bibliography: First and foremost journal endeavours to offer a reaction, from a general point of view, to the inquiry of how culture uncovers itself in the application of qualitative research in intercultural communication. When we come across the expression culture it is most important to remember that culturally credited social cooperation methods are themselves the after effect of socially built methodologies. They are some piece of an individual-aggregate persuasion with numerous potential implications, which are rising and in steady reformulation from a wide collection of social and cultural points of view. A significant part of the research in intercultural correspondence has been administered towards the investigation of these frameworks of socially related implications. it offers the role of culture in communication among diversified people (Aneas and Sandà ­n, 2009). In the first referenced journal. an inquiry is tended to that how culture is conceptualized and shows itself in the application of qualitative system. With this goal we endeavour to summarize the research done from the field of intercultural and diverse communication which we feel may be of assistance in moving towards the important conceptualization in an essay. It is additionally kept in mind while writing the essay that the points discussed here will empower us to investigate, from a general viewpoint, the relationship between culture and probably the most critical parts of qualitative exploration (Adamopolous, 2011). The second journal used for doing an essay discuss some of the important thing out of which few points are discussed here in abstractive form. The globalized world nowadays is identified by an always developing number of contacts bringing about correspondence between individuals with diverse etymological and social foundations. This correspondence happens in view of contacts inside the territories of business, military collaboration, science, instruction, mass-media, and diversion, tourism additionally as a result of migration realized by work lack or political clashes. In all these contacts, there is cultural communication which needs to be as useful as could be expected under the circumstances, without mistaken assumptions and breakdowns. It is our conviction that exploration on the way of semantic and cultural similitude and contrasts here can play a positive and productive part(Allwood, 2014). Third research journal discuss more about intercultural communication in a brief way which is summarized here as we have now started to see that there is not a solitary, basic meaning of culture and that, indeed, distinctive journalists characterize culture in truly diverse courses (as variable, as capacity, as procedure, as force). Actually, how one sees and studies culture, a few scholars say, has moral ramifications some individuals see the way others study. Intercultural correspondence truly implies that when individuals from two separate societies correspond with one another. Numerous researchers have decided to break intercultural communication research into two primary sorts, generally like Emic and Etic. Essentially emic incorporates a research that focus on a culture from that cultures own particular viewpoint, typically intimating the utilization of perception, qualitative, or other open-ended exploration to confirm that point of view while etic is the research done that uses an external theories or general systematic frameworks to translate the code of conduct, world perspective, and so on., in a specific culture (Baldwin, 2004). Fourth journal article discuss by arguing that that the intercultural communication is critical to be considered in universal organizations as it analyses how individuals from distinctive cultures, convictions and religions meet up to work and correspond with one another. Need for understanding and adopting intercultural communication is expanding as more organizations go worldwide or global. They understand that there are obstructions and confinements when entering an outside domain. Without the assistance of intercultural communications they can unknowingly cause perplexity and make sever mistakes. For these intercultural organizations to rupture the social obstructions experienced when going into international grounds it is key for them to completely comprehend the cultural contrasts that exist to stop harming business relations because of gaps among people due to intercultural communication. There are numerous speculations that standardized some rules to help in the understanding of intercultural communication. These rules help in preventing ignorance between diversified cultural gatherings which results due to misunderstanding lack of knowledge (Kwintessential.co.uk, 2014). Fifth journal used to write an essay is written is Yanhong Hu in which he says that the increasing rate globalization in the world has expanded individuals need to be included in worldly activities in such fields as education, business, pharmacy, religion and even the military. Indeed, individuals with diverse cultural foundations are getting to be more related on one another, and the term intercultural communication is no more new to them. Keeping in mind the end goal to instruct individuals to create sense of understanding for respect of cultures of one another and outfit them with powerful and proper relational abilities in their intercultural experiences, the scholarly research of intercultural communication has developed and excited dynamic enthusiasm among analysts in this field. Numerous researchers and specialists have wandered profound into the field and created a interesting different themes identified with intercultural communications. Rather than the inspecting and investigating so many published books, articles peer-reviewed journals, there is moderately minimal precise data on the flow pattern of intercultural communication research at both local international levels. Locally, a few researchers have done some general research about the facts on intercultural communication. Though those studies may be instructive, they give off an impression of being generally individual perspectives and recommendations but not based on information based data. Two related studies are directed separately by ShiyongPeng (2005) and Wenzhong Hu (2005). His article on the exploration of intercultural communication is information based; on the other hand, what is needed to be discussed in this article is the detailed studies of the locally-based information demonstrating what sort of methodologies are adopted in their papers by Chinese intercultural communication specialists which is the thing that this study means to analyse (Hu, 20 10). References: Aneas, M. and Sandà ­n, M. (2009). Intercultural and Cross-Cultural Communication Research: Some Reflections about Culture and Qualitative Methods.Forum Qualitative Sozialforschung / Forum: Qualitative Social Research, [online] 10(1). Available at: http://www.qualitative-research.net/index.php/fqs/article/view/1251/2738 [Accessed 6 Sep. 2014]. Adamopolous, John Lonner, Walter (2001). Culture and psychology at a crossroad: Historical perspective and theoretical analysis. In David Matsumoto (Ed.),The handbook of culture and psychology(pp.11-34). New York: Oxford University Press. Allwood, J. (2014). Journal of Intercultural Communication, (35). Baldwin, J. (2004). Assumptions behind communication theories: Reality, knowledge, and values., pp.21-34. Kwintessential.co.uk, (2014). An Introduction to Intercultural Communication | articles | cultural services. [online] Available at: http://www.kwintessential.co.uk/cultural-services/articles/introduction-intercultural.html [Accessed 7 Sep. 2014]. Hu, Y. (2010). International Journal of Intercultural Relations, (35), pp.554-555.

War Against Boys :: essays research papers

War Against Boys: Fact or Fiction   Ã‚  Ã‚  Ã‚  Ã‚  One of the oldest debates in psychology is the nature versus nurture debate. Its roots extend far beyond the nineteenth century psychologists such as Freud and Skinner into the beginnings of scientific thought. Even Greek philosophers such as Aristotle and Plato addressed the issue of how personality is formed. Today, a relative consensus has been reached that nature and nurture work in tangent with one another; one can have many biological possibilities of which the environment determines the development. In any area involving gender however, this debate is still strong. In the War Against Boys: How misguided feminism is harming our young men, Christina Hoff Sommers points out that some feminists still support the nurture side of the debate without acknowledging any possibility of a biological influence. Sommers insists on examining the growing number of studies indicating that gender differences are not all socialized but are biological sex differences, just as differences in physiology between the sexes are biologically based. However, in her efforts to show how misguided feminism has become in its search for gender equality, Sommers takes the other extreme of the debate and discounts any differences formed during socialization. Although literature for the biological explanation of gender construction is growing, one cannot discount the environmental influences as Sommers does. A Biological Explanation   Ã‚  Ã‚  Ã‚  Ã‚  If there is one aspect of research in sex differences to which Sommers does justice, it is the research supporting the differing biology of males and females. She convincingly summarizes the evidence for the biological influence in a clear, concise manner. First, she addresses the cognitive abilities with which a large difference has been shown to favor males or females. Males are on the whole superior to females in visuospatial abilities, especially mental rotation tasks (Halpern, 1992). In fact, Sommers doesn’t mention this, but the effect size found in this area of sex differences is one of the largest that psychologists study in any field with an effect size of d=0.9 (Halpern, 1992). While not the best at visuospatial skills, females are superior in their verbal skills especially â€Å"writing, retrieval from long-term memory, and verbal articulation tasks† (Halpern, 1992). These cognitive differences do not suppose a cause however. They could arise not from biology, but from socialization as the feminists argue.   Ã‚  Ã‚  Ã‚  Ã‚  To prove a biological cause is implicated, Sommers has to draw on research that connects biology such as hormones or structural differences to related behaviors and preferences.